Audio level is too high at some point in the path (Clipping)
Is it present when nothing is playing? Or only during Playback
If when nothing is playing, probably a ground loop (60Hz electrical hum), short or interference.
If only during playback, it could be a short/overload in signal path, blown driver, foreign object on the enclosure, etc.
Does it sit under the audio, or does it distort the audio
If under, probably a ground loop.
If the audio is being distorted, could be the amp is overdriving (loud sounds are being clipped – sound like they are buzzing, but softer sounds are OK), could be a blown or detached driver (causes a “thwump or other odd sound in playback), something touching the speaker box and rattling.
From where in the auditorium is it coming?
If we can determine which speaker, that is ideal (Left stage, 2nd Right surround on the wall, etc.)
If not, the general area is still beneficial (behind the screen, right side of the auditorium, etc.)